Recent methodology advances in fluorescence molecular tomography

作     者：Yu An Kun Wang Jie Tian 

作者机构：Key Laboratory of Molecular ImagingInstitute of AutomationChinese Academy of SciencesBeijingChina 

出 版 物：《Visual Computing for Industry,Biomedicine,and Art》 (工医艺的可视计算（英文）)

年 卷 期：2018年第1卷第1期

页      面：1-11页

核心收录：

学科分类：0502[文学-外国语言文学] 1303[艺术学-戏剧与影视学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1301[艺术学-艺术学理论] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 0835[工学-软件工程] 0811[工学-控制科学与工程] 0503[文学-新闻传播学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 10[医学] 

基　　金：supported by Ministry of Science and Technology of China under Grant No.2017YFA0205200,2016YFC0103702 National Natural Science Foundation of China under Grant No.81227901,81527805‘Chinese Academy of Sciences under Grant No.GJJSTD20170004’Beijing Municipal Science&Technology Commission No.Z161100002616022 by the General Financial Grant from the China Postdoctoral Science Foundation under Grant 2017 M620952 

主　　题：Fluorescence molecular tomography Image reconstruction Photon propagation model Forward problem Inverse problem 

摘      要：Molecular imaging(MI)is a novel imaging discipline that has been continuously developed in recent *** combines biochemistry,multimodal imaging,biomathematics,bioinformatics,cell&molecular physiology,biophysics,and pharmacology,and it provides a new technology platform for the early diagnosis and quantitative analysis of diseases,treatment monitoring and evaluation,and the development of comprehensive *** Molecular Tomography(FMT)is a type of optical imaging modality in MI that captures the three-dimensional distribution of fluorescence within a biological tissue generated by a specific molecule of fluorescent material within a biological *** with other optical molecular imaging methods,FMT has the characteristics of high sensitivity,low cost,and safety and *** has become the research frontier and research hotspot of optical molecular imaging *** paper took an overview of the recent methodology advances in FMT,mainly focused on the photon propagation model of FMT based on the radiative transfer equation(RTE),and the reconstruction problem solution consist of forward problem and inverse *** introduce the detailed technologies utilized in reconstruction of ***,the challenges in FMT were *** survey aims at summarizing current research hotspots in methodology of FMT,fromwhich future research may benefit.