影响海德堡眼底照相机和海德堡眼底照相机Ⅱ测试-再测试结果变异性的因素
Factors affecting the test-retest variability of Heidelberg retina tomograph and Heidelberg retina tomograph II measurements作者机构：Dr. Glaucoma Research Unit Moorfields Eye Hospital 162 City Road London EC1V 2PD United Kingdom
出 版 物：《世界核心医学期刊文摘(眼科学分册)》 (Digest of the World Core Medical Journals)
年 卷 期：2006年第4期
页 面：34-35页
学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学]
摘 要：Aims: To evaluate the test-retest variability of stereometric parameter measurements made with the Heidelberg retina tomograph (HRT) and Heidelberg retina tomograph -II (HRT-II), and to establish which parameter(s) provided the most repeatable and reliable measurements with both devices. An investigation into the factors affecting the repeatability of the measurements of this parameter(s) was conducted. Methods: 43 ocular hypertensive and 31 glaucoma subjects were recruited to a test-retest study. One eye from each subject underwent HRT and HRT-II imaging by two observers on each of two occasions within 6 weeks of each other. Lens grading was carried out by LOCS III grading and Scheimpflug camera generated densitogram analysis. Results: Rim area (RA) and mean cup depth measurements were found to be least variable. Both inter-test reference height difference and image quality had a strong relation (R2 0.5, p 0.0001) with inter-test RA difference and, together, are responsible for 70%of RA measurement variability. Image quality was influenced by lens opacity, cylindrical error, and age. Inter-test RA measurement differences were unrelated to the observer or visit interval. Conclusions: RA represents an appropriate measure for monitoring glaucomatous progression. Reference height difference and image quality were the factors thatmost influenced RA measurement variability. Image analysis strategies that address these factors may reduce test-retest variability.
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