When lifestyles sign
作者机构:HepatologyDepartment for BioMedical ResearchUniversity of BernBernSwitzerland GastroenterologyDepartment of Clinical Medicine and SurgeryUniversity of Naples“Federico II”NaplesItaly University Institute of Clinical ChemistryInselspitalUniversity of BernBernSwitzerland University Clinic of Visceral Surgery and MedicineInselspital BernBernSwitzerland
出 版 物:《Hepatobiliary Surgery and Nutrition》 (肝胆外科与营养(英文))
年 卷 期:2019年第8卷第1期
页 面:69-71页
核心收录:
学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
摘 要:Nonalcoholic fatty liver disease(NAFLD)has a global prevalence of 25%,reflecting the global epidemic of obesity and diabetes(1).The onset and development of NAFLD are closely associated with dietary habits and lifestyle;consequently,lifestyle modifications including weight loss,increased physical activity,and dietary changes remain the treatment of choice for *** when drugs to treat non-alcoholic steatohepatitis will be available,lifestyle changes will remain an essential component of the therapeutic plan of these *** the last years,a strong association between lifestyle and hepatocellular carcinoma(HCC)has become evident(2-4).In patients with NAFLD,the annual incidence of HCC is 0.44 per 1,000 person/year and almost 50%of cases develops in a non-cirrhotic liver resulting in a diagnosis at an advanced stage with a worse prognosis(1,5).Nonetheless,the high prevalence of NAFLD with the relatively low risk for HCC makes a surveillance program cost-ineffective in non-cirrhotic patients(6).