Epidemiology and management of hepatitis C virus infections in immigrant populations

作     者：Nicola Coppola Loredana Alessio Lorenzo Onorato Caterina Sagnelli Margherita Macera Evangelista Sagnelli Mariantonietta Pisaturo Coppola Nicola;Alessio Loredana;Onorato Lorenzo;Sagnelli Caterina;Macera Margherita;Sagnelli Evangelista;Pisaturo Mariantonietta

作者机构：Department of Mental Health and Public MedicineSection of Infectious DiseasesUniversity of CampaniaVia:L.Armanni 580131 NaplesItaly Infectious Diseases UnitAORN Sant'Anna e San Sebastiano di Caserta81100 CasertaItaly 

出 版 物：《Infectious Diseases of Poverty》 (贫困所致传染病（英文）)

年 卷 期：2019年第8卷第2期

页      面：13-22页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

基　　金：the study"Evaluation of an innovative model to eliminate HG/infection in a high-risk population of undocumented migrants and low-income refugees"(EUDRACT:2017-001024-21) 

主　　题：HCV infection Chronic hepatitis C immigrant Directly acting antiviral agent Low-income country 

摘      要：Background:At present,there is a continuous flow of immigrants from the south of the world to north-western *** immigrants originate from areas of high-prevalence of viral hepatitis and pose a challenge to the healthcare systems of the host *** of this study is to evaluate the prevalence and virological and clinical characteristics of hepatitis C virus(HCV)infection in immigrants and the strategies to identify and take care of the immigrants infected with *** body:We conducted an electronic literature search in several biomedical databases,including PubMed,Google Scholar,Scopus,Web of Science,using different combinations of key words:HCV infection;chronic hepatitis C,immigrants;low-income countries.We included studies written in English indicating the epidemiological data of HCV infection in the immigrant population,studies that assessed the clinical presentation,clinical management and treatment with directly acting antiviral agent in immigrants,HCV infection is unevenly distributed in different countries,with worldwide prevalence in the general population ranging from 0.5 to 6.5%.In Western countries and Australia this rate ranges from 0.5 to 1.5%,and reaches 2.3%in countries of south-east Asia and eastern Mediterranean regions,3.2%in China,0.9%in India,2.2%in Indonesia and 6.5%in Pakistan;in sub-Saharan Africa the prevalence of HCV infection varies from 4 to 9%.Immigrants and refugees from intermediate/high HCV endemic countries to less-or non-endemic areas are more likely to have an increased risk of HCV infection due to HCV exposure in their countries of *** of the high HCV endemicity in immigrant populations and of the high efficacy of directly acting antiviral agent therapy,a campaign could be undertaken to eradicate the infection in this ***:The healthcare authorities should support screening programs for immigrants,performed with the help of cultural mediators and including educational aspects to break