Herbal Medicines Prevent the Development of Atopic Dermatitis by Multiple Mechanisms

作     者：MAN Mao-qiang HU Li-zhi Peter M.Elias 

作者机构：Dermatology ServiceVeterans Affairs Medical Center Department of DermatologyUniversity of California San Francisco School of Basic Medical SciencesTianjin Medical University 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2019年第25卷第2期

页      面：151-160页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1005[医学-中医学] 1002[医学-临床医学] 10[医学] 

基　　金：Supported by the National Institute of Health,USA(No.AR061106) Veterans Affairs Medical Center,USA(No.VA Merit-1 101BX000608) National Eczema Association,and National Science Foundation of China(No.81301360) 

主　　题：herbal medicines T cells cytokines permeability barrier dermatitis 

摘      要：Atopic dermatitis(AD) is among the most common skin disorders in humans. Although a variety of regimens are available for the treatment of AD, preventive approaches are limited. Recent studies have demonstrated that certain naturally-occurring herbal medicines are effective in preventing the development of AD via divergent mechanisms, such as inhibiting cytokine and chemokine expression, IgE production, inflammatory cell infiltration, histamine release, and/or enhancement of epidermal permeability barrier function. Yet, they exhibit few adverse effects. Since herbal medicines are widely available, inexpensive and generally safe, they could represent an ideal approach for preventing the development of AD, in both highly developed and developing countries.