A DLM/FD/IB Method for Simulating Cell/Cell and Cell/Particle Interaction in Microchannels

作     者：Tsorng-Whay PAN Roland GLOWINSKI 

作者机构：Department of Mathematics University of Houston 

出 版 物：《Chinese Annals of Mathematics,Series B》 (数学年刊（B辑英文版）)

年 卷 期：2010年第31卷第6期

页      面：975-990页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

基　　金：supported by the National Science Foundation of the United States (Nos. ECS-9527123  CTS-9873236  DMS-9973318  CCR-9902035  DMS-0209066  DMS-0443826  DMS-0914788) 

主　　题：Red blood cells Elastic spring model Margination Fictitious domain method Immersed boundary method Microchannel 

摘      要：A spring model is used to simulate the skeleton structure of the red blood cell (RBC) membrane and to study the red blood cell (RBC) rheology in Poiseuille flow with an immersed boundary method. The lateral migration properties of many cells in Poiseuille flow have been investigated. The authors also combine the above methodology with a distributed Lagrange multiplier/fictitious domain method to simulate the interaction of cells and neutrally buoyant particles in a microchannel for studying the margination of particles.