Vitamin D axis: a new target for treatment depression via tonifying kidney of chinese medicine
Vitamin D axis: a new target for treatment depression via tonifying kidney of chinese medicine作者机构：School of Preclinical Medicine Guiyang University of Chinese Medicine Guiyang Guizhou China Experiment Center Guiyang University of Chinese Medicine Guiyang Guizhou China
出 版 物：《TMR Theory and Hypothesis》 (TMR理论与假说)
年 卷 期：2018年第1卷第4期
页 面：99-105页
学科分类：10[医学]
基 金：National Natural Science Foundation of China (No. 81874376, No. 81460694, No.81760841) Project of Education Department of Guizhou Province (K041, KY172) Natural Science Foundation of Science and Technology Department of Guizhou Province (1401)
主 题：Vitamin D Axis Depression Tonifying Kidney of Chinese Medicine
摘 要：Accumulating data indicate that kidney tonifying recipe to treat depression patients may significantly reduce clinical symptoms, effectively improve the quality and prognosis of the patient s life. Clinical and experimental studies have suggested that tonifying kidney recipe has multiple targets, and thereby via multiple ways to accomplish antidepressant effect. The tonifying kidney recipe has been used in traditional Chinese medicine to control neurotrophic factor so as to promote the growth, differentiation, maturation of neurons. The tonifying kidney recipe participates in protection of neural plasticity, brain development, immune regulation, and a variety of other physiological processes to act as an antidepressant that has great similarity as vitamin D axis. In this article, we describe the current knowledge to introduct the relationship between kidney deficiency and vitamin D axis, and speculate about the molecular mechanism of tonifying kidney recipe in the treatment of depression by regulating vitamin D axis.
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