Synthesis and Anticancer Effect of gem-Difluoromethylenated Chrysin Derivatives
Synthesis and Anticancer Effect of gem-Difluoromethylenated Chrysin Derivatives作者机构:Institute of Pharmacy & Pharmacology Nanhua University Hengyang 421001 Cancer Research Institute Nanhua University Hengyang 421001
出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期:2006年第17卷第11期
页 面:1439-1442页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 0703[理学-化学] 10[医学]
主 题:Anticancer activity gem-difluoromethylenated chrysin.
摘 要:Ten gem-difluoromethylenated chrysin derivatives were prepared and their anticancer activities in vitro were evaluated by the standard MTT method. The results of biological test showed that some of gem-difluoromethylenated chrysin derivatives had higher anticancer activity than chrysin.