Study on Alkaloids in Fructus Hordei Germinatus
Study on Alkaloids in Fructus Hordei Germinatus作者机构:School of PharmacySouthwest Minzu University Alar First Division of Institute for Food and Drug Control Key Laboratory of Resource Protection and Utilization of Tarim BasinXinjiang Production & Construction Ethnic Medicine InstituteSouthwest Minzu University
出 版 物:《Medicinal Plant》 (药用植物:英文版)
年 卷 期:2018年第9卷第6期
页 面:19-22页
学科分类:10[医学]
主 题:Fructus Hordei Germinatus Alkaloids Ultra high performance liquid chromatography(UPLC) Mass spectrometer(MS) Preparative high performance liquid chromatography(pHPLC)
摘 要:[Objectives]To isolate and analyze alkaloids in Fructus Hordei Germinatus.[Methods]The alkaloids in the Fructus Hordei Germinatus were extracted by ultrasonic technology,and analyzed by the ultra-performance liquid chromatography tandem mass spectrometry(UPLC-MS/MS) technique.[Results] According to the mass spectrometry information,compared with the literature reports,the possible structures of seven alkaloids in the Fructus Hordei Germinatus could be *** 1,2 and 3 were organic amine alkaloids,respectively tyramine and N-methyltyramine,hordenine,compounds 4,5,6 and 7 were indole alkaloids,respectively,tryptamine,gramine,harmine,and *** alkaloids in the Fructus Hordei Germinatus were separated by preparative high performance liquid chromatography(p HPLC) technique,a compound was obtained and identified by UPLC-MS/MS and nuclear magnetic resonance(NMR) technique as hordenine.[Conclusions]This experiment is expected to lay a foundation for the development of alkaloids in the Fructus Hordei Germinatus.