MRI-determined fat content of human liver,pancreas and kidney
MRI-determined fat content of human liver,pancreas and kidney作者机构:Department of RadiologyUniversity Medical Center Groningen and University of Groningen Department of EpidemiologyUniversity Medical Center Groningen and University of Groningen Department of Internal MedicineUniversity Medical Center Groningen and University of Groningen
出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))
年 卷 期:2010年第16卷第16期
页 面:1993-1998页
核心收录:
学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术(可授医学、理学学位)] 10[医学]
主 题:Lipids Magnetic resonance imaging Magnetic resonance spectroscopy Kidney Liver Pancreas
摘 要:AIM:To assess and correlate the lipid content of various organs in obese subjects and in persons with a normal body ***:Magnetic resonance spectroscopy and a previously validated gradient echo magnetic resonance imaging method with Dixon s two point technique were used in this study to quantify fat in liver,pancreas as well as ***:In 36 volunteers with body mass index(BMI) ranging from 20.0 to 42.9 kg/m2,the median fat content of liver,pancreas and kidney was 2.3%(interquartile range:0.2%-7.8%),2.7%(1.0%-6.5%) and 0.7%(0.1%-1.4%),*** and subcutaneous fat correlated significantly with liver and pancreas fat *** show for the first time the significant correlation of liver and pancreas fat content in healthy controls(r = 0.43,P 0.01).These observations are related to body weight as measured by BMI and the amount of subcutaneous *** fat content is very low and correlates with none of the other fat ***:Renal lipid accumulation,unlike the coupled accumulations of fat in liver and pancreas,is not observed in obese *** suggestions made in previous studies,renal lipid accumulation appears not to be involved in the pathogenesis of renal disease in humans.