Observational Study of Chinese Medicine Syndrome Distribution in Patients with Acute Myocardial Infarction and Its Impact on Prognosis

作     者：ZHU Hong-min ZHOU Jing-min JIN Xue-juan FU Ming-qiang ZHU Ling-ti CUI Xiao-tong FAN Yue CAI Ding-fang GE Jun-bo 

作者机构：Department of CardiologyZhongshan HospitalFudan UniversityShanghai (200032)China Department of Integrated Traditional and Western MedicineZhongshan HospitalFudan UniversityShanghai (200032)China 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：2019年第25卷第11期

页      面：825-830页

核心收录：

学科分类：10[医学] 

基　　金：Supported by the National Basic Research Program of China(No.2012CB518605) Science and Technology Innovative Program of Shanghai,China(No.10DZ1975400) 

主　　题：acute myocardial infarction Chinese medicine syndrome prognosis 

摘      要：Objective: To investigate the distribution of Chinese medicine (CM) syndrome in patients with acute myocardial infarction (AMI) on admission and its impact on prognosis. Methods: A total of 525 AMI patients were prospectively recruited and classified into 4 groups based on their clinical characteristics: excess-heat, excess-cold, deficiency-heat and deficiency-cold syndromes. Major adverse cardiovascular events (MACEs) were followed up. Results: The excess syndrome was more common than deficiency syndrome (72.95% vs. 27.05%;P0.05). Totally 495 (94.29%) of 525 AMI patients were followed up (median 277 days). There were 59 (11.92%) MACEs. After adjusted with confounding factors in Cox regression models, the hazard ratio (95% confidence interval) of excess-heat, excess-cold, deficiency-heat and deficiency-cold syndrome groups were 1, 1.25 (0.63, 2.49;P0.05), 2.37 (1.14, 4.94;P0.05), 3.76 (1.71, 8.28;P0.05), respectively. Conclusions: Excess syndrome was more common in AMI patients and had better prognosis, while deficiency-cold syndrome had the poorest prognosis. CM syndrome was of value in predicting long-term outcomes in AMI patients.