High HbA1c is associated with higher risk of ischaemic stroke in Pakistani population without diabetes

作     者：Ali Zohair Nomani Sumaira Nabi Shahzad Ahmed Mansoor Iqbal Haris Majid Rajput Suhail Rao 

作者机构：Department of NeurologyPakistan institute of Medical SciencesIslamabadPakistan 

出 版 物：《Stroke & Vascular Neurology》 (卒中与血管神经病学（英文）)

年 卷 期：2016年第1卷第3期

页      面：133-139页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：diabetes cholesterol cardiovascular 

摘      要：Context:The role of glycated haemoglobin(HbA1c)in the prediction of ischaemic stroke in individuals without diabetes is ***:We performed a study to analyse the role of HbA1c in the risk prediction of ischaemic stroke in Pakistani population without *** further studied the difference between HbA1c values of individuals with diabetes and without diabetes with *** and design:Single centre,case–*** and methods:In phase I,a total of 233 patients without diabetes with ischaemic stroke and 245 as controls were *** of HbA1c levels,lipid profiles and blood pressure recordings with ischaemic stroke was *** phase II,comparison was done between diabetics and nondiabetics with *** analysis:Comparison of the mean variables was performed with Student’s *** regression analysis with ischaemic stroke as the dependent variable was performed for phase ***:In phase I,the ischaemic stroke group had significantly higher HbA1c levels(5.9±2.9%vs 5.5±1.6%)compared with controls(p0.05).Conclusions:Higher HbA1c indicated a significantly increased risk for ischaemic *** HbA1c value above 5.6%(prediabetic range)predicted future risk of stroke and efforts to maintain glucose level within the normal range(≤5.6%)in individuals with high cardiovascular risk are important.