Influence of HBcAg in liver cell plasma on expression of transforming growth factor-beta 1 in liver tissue of low-grade chronic hepatitis B patients

作     者：Yong-Gang Liu Jian-Hua Lu Xin-Xin Wang Jian-Lin Yang Zhen-Wei Lang Xin Meng Shi-Jie Zhang Lin Sun Jun-Qiang Li Chen-Zhao Song 

作者机构：Department of Clinical Hepatitis TianjinInfectious Disease Hospital Tianjin 300192 China Shijiazhuang No. 5Hospital Shijiazhuang 050021 Hebei Province China Laboratory of Pathology Capital Medical University AffiliatedYouan Hospital Beijing 100054 China 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2006年第12卷第1期

页      面：127-129页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by the Beijing Science and Technology Commission No.H020920020290 

主　　题：HBcAg Factor-beta 1 Chronic hepatitis B 

摘      要：AIM： To study the influence of HBcAg on the expression of transforming growth factor-beta 1 （TGF-131） in liver tissue of low-grade chronic hepatitis B （CHB） patients. METHODS： The expression of T（3F-β1 and HBcAg in liver samples from 93 low-grade CHB patients was detected by immunohistochemistry and valuated by semi-quantitative scoring. RESULTS： In the 93 low-grade CHB patients, HBcAg was expressed in cell plasma but not in the liver tissue. There was no significant difference between the two groups. CONCLUSION： The expression of TGF-β1 is not related with HBcAg expressed as plasma type in the tissues of low-grade CHB patients.