Dynamic infusion cavernosometry and cavernosography for classifying venous erectile dysfunction and its significance for individual treatment

作     者：Qing-Qiang Gao Jian-Huai Chen Yun Chen Tao Song Yu-Tian Dai 

作者机构：Department of AndrologyNanjing Drum Tower HospitalAffiliated Hospital of Nanjing University Medical SchoolNanjingJiangsu 210008China Department of AndrologyJiangsu Province Hospital of Chinese MedicineAffiLiated Hospital of Nanjing University of Chinese MedicineNanjingJiangsu 210029China. 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2019年第132卷第4期

页      面：405-410页

核心收录：

学科分类：10[医学] 

基　　金：the grants from the National Natural Science Foundation of China (No.81701433) the Project of Nanjing Municipal Bureau of Health (No. YKK17098) the Fundamental Research Funds for the Central Universities (No.021414380134) 

主　　题：Venous erectile dysfunction Dynamic infusion cavernosometry and cavernosography Diagnosis Treatment 

摘      要：Background: The precise pathophysiology of venous erectile dysfunction (VED) was still unclear. Dynamic infusion cavernosometry and cavernosography (DICC) was the gold standard approach for the diagnoses of VED. However, a standard operative procedure of DICC was needed and it was unclear whether DICC could show promise in accurate assessment and treatment of VED. The aim of this study was to establish an optimized operation process of DICC and evaluate the efficacy of DICC in the diagnoses and therapy of VED. Methods: One hundred and forty-seven VED patients identified by the color doppler duplex ultrasonography (CDDU) were included. Then the method of DICC was adopted to assess the severity of VED and all patients were divided into 4 groups, including (1) non-VED;(2) mild VED;(3) moderate VED and (4) severe VED. All patients received the treatment of psychotherapy. Drug therapy, the intervention embolism of corpus cavernosum and the implantation of penile prosthesis were applied if psychotherapy was ineffective for patients. The international index of erectile function (IIEF-5) scores of patients were collected and compared before and after treatment. Results: IIEF-5 score of non-VED group after psychotherapy (19.35 ± 3.59) and drug therapy (23.31 ± 0.75) was higher than that before psychotherapy (15.30 ± 2.72, t=-4.31, P 0.05). IIEF-5 score of severe VED group was increased under the treatment of implantation of penile prosthesis (23.25 ± 0.71) compared with that bef