Three New Humulane Sesquiterpenes from Cultures of the Fungus Antrodiella albocinnamomea

作     者：Zi-Ming Chen Qiong-Ying Fan Xia Yin Xiao-Yan Yang Zheng-Hui Li Tao Feng Ji-Kai Liu 

作者机构：State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming Institute of BotanyChinese Academy of Sciences132#Lanhei RoadHeilongtanKunming 650201YunnanPeople’s Republic of China College of Life ScienceHebei Normal UniversityShijiazhuang 050024People’s Republic of China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2014年第4卷第4期

页      面：207-211页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：National Natural Science Foundation of China(U1132607,81373289,81102346) Youth Innovation Promotion Association of CAS(2011312D11019) 

主　　题：Antrodiella albocinnamomea Humulane-type sesquiterpenes Protein tyrosine phosphatase inhibitory activity 

摘      要：Three new humulane-type sesquiterpenes,antrodols A–C(1–3),were isolated from cultures of the fungus Antrodiella *** structures were elucidated on the basis of extensive spectroscopic *** A–C(1–3)are first examples of humulane-type sesquiterpenes isolated from cultures of higher fungi,and antrodol A(1)was the first report of humulane-type sesquiterpene with a methyl rearranged at *** compounds were evaluated in the enzyme inhibition assay against two protein-tyrosine phosphatases(PTPs):MEG2 and PTP1Bc.