Morphological,kinetic,membrane biochemical and genetic aspects of intestinal enteroplasticity

作     者：Laurie A Drozdowski M Tom Clandinin Alan BR Thomson 

作者机构：Medical Affairs Mead Johnson Nutritionals Department of AgricultureFood and Nutritional SciencesUniversity of Alberta Division of Internal MedicineDepartment of MedicineUniversity of Alberta 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2009年第15卷第7期

页      面：774-787页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Diabetes Diet Hormonal regulation Intestinal resection Mechanisms Morphology Nutrientabsorption Short bowel syndrome Signals 

摘      要：The process of intestinal adaptation(enteroplasticity) is complex and *** a number of trophic nutrients and non-nutritive factors have been identified in animal studies,successful,reproducible clinical trials in humans are *** mechanisms underlying this adaptive process may direct research toward strategies that maximize intestinal function and impart a true clinical benefit to patients with short bowel syndrome,or to persons in whom nutrient absorption needs to be *** this review,we consider the morphological,kinetic and membrane biochemical aspects of enteroplasticity,focus on the importance of nutritional factors,provide an overview of the many hormones that may alter the adaptive process,and consider some of the possible molecular *** most of the data is derived from rodent studies,wherever possible,the results of human studies of intestinal enteroplasticity are provided.