曲利本蓝与阿米卡星相互作用的共振瑞利散射光谱及其应用
Study on the interaction of amikacin with trypan blue by resonance rayleigh scattering spectrum and its application作者机构：遵义医学院药学系贵州遵义563003
出 版 物：《化学研究与应用》 (Chemical Research and Application)
年 卷 期：2008年第20卷第8期
页 面：1043-1046页
核心收录：
学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学]
摘 要：In weak acid medium,a significant enhancement of resonance Rayleigh scattering(RRS) spectrum and new RRS spectra were observed when amikacin reacted with acid bisazo dye trypan blue and new RRS spectra with amaximum peak at *** characteristic of RRS spectra,the optimum conditions for the reaction and the influencing factors were *** concentration of amikacin in the range of 0～6.24μg/mL is linear to the resonance scattering intensity(IRRS)at *** detection limit(3σ) of this method for Amikacin Sulphate is 9.2 ng·***,a simple,high sensitivity,good selectivity and repeat method for the determination of Amikacin Sulphate injection samples by RRS is developed with satisfactory results.
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