Complete Genomic Sequence of a Chinese Isolate of Duck Hepatitis Virus
Complete Genomic Sequence of a Chinese Isolate of Duck Hepatitis Virus作者机构:Institute of Virology and Biotechnology Zhejiang Academy of Agricultural Sciences Hangzhou 310021 China College of Animal Science and Technology Anhui Agriculture University Hefei 230036 China
出 版 物:《中国病毒学》 (Virologica Sinica)
年 卷 期:2007年第22卷第5期
页 面:353-359页
核心收录:
学科分类:090601[农学-基础兽医学] 09[农学] 0906[农学-兽医学]
基 金:National Natural Science Foundation of China (30670074)
摘 要:The complete genomic sequence of Duck hepatitis virus 1(DHV-1) ZJ-V isolate was sequenced and determined to be 7 691 nucleotides(nt) in length with a 5 -terminal un-translated region(UTR) of 626 nt and a 3 -terminal UTR of 315 nt(not including the poly(A) tail).One large open reading frame(ORF) was found within the genome(nt 627 to 7 373) coding for a polypeptide of 2 249 amino *** data also showed that the poly(A) tail of DHV-1 has at least 22 A *** comparison revealed significant homology(from 91.9% to 95.7%) between the protein sequences of the ZJ-V isolate and those of 21 reference *** DHV-1 has been classified as an unassigned virus in the Picornaviridae family,its genome showed some unique ***-1 contains 3 copies of the 2A gene and only 1 copy of the 3B gene,and its 3 -NCR is longer than those of other *** analysis to do sequence homology based on the VP1 protein sequences showed that the ZJ-V isolate shares high sequence homology with the reported DHV-1 isolates(from 92.9% to 99.2%),indicating that DHV-1 is genetically stable.