肌酸激酶MB——儿童良性阵发性眩晕新的诊断标记物
Creatine kinase MB (CK- MB) in benign paroxysmal vertigo of childhood: A new diagnostic marker作者机构:Department of Pediatrics Falun Hospital 791 82 Falun Sweden Dr.
出 版 物:《世界核心医学期刊文摘(儿科学分册)》 (Dkgest of the World Latest Medical Information)
年 卷 期:2005年第1卷第8期
页 面:38-38页
学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
摘 要:Objectives: To evaluate the relation between creatine kinase- MB (CK- MB) a nd benign paroxysmal vertigo in childhood (BPV). Study design: We prospectively evaluated and followed serum CK- MB in 22 children with BPV diagnosed between 1 998 and 2003. Results: The average age of debut for BPV was 1.7 years, and follo w- up time was 2.8 years. The CKMB values were elevated in all children. CK- M B values were persistently increased (mean, 6.0 μ g/L) during the study period and were not related to duration of BPV, time since last attack, or frequency of attacks. CK- MB became normal in 7 children who recovered during the study per iod. After the initial increased CK- MB value, CK, aspartate aminotransferase, and cardiac troponin I (in 16 children) were measured as markers of muscular dis ease. CK was slightly increased in 7 (31.8% ) and aspartate aminotransferase in 14 (63.6% ) of the children. Cardiac troponin I was normal in all children. Co nclusions: In this study, serum CK- MB levels were associated with BPV. These f indings indicate a possible muscular involvement in BPV. Fur- ther studies will be needed to determine if CK- MB is useful as a diagnostic test for BPV.