A CONVENIENT SYNTHESIS OF NEW HYDROXYL CYCLIC AZA COMPOUNDS

作     者：Guo Ping XUE Sheng Hua LIU En Qin FU Han Sheng XU and Cheng Tai WU (Department of Chemistry, Wuhan University, Wuhan 430072) 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1994年第5卷第6期

页      面：457-458页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

摘      要：A convenient synthetic route to a series of hydroxyl cyclic di- and tri-aza compounds was described. Condensation of 1, 3-dichloropropanol[2] with the appropriate disodium salts of N-tosylated di-and triamine in EtOH gave the corresponding 7-, 8- and 10-membered di- and triamine cycles in reasonable yields. The tosyl groups were removed with 33%HBr-HOAc in ca.90% yields.