Clinical Study on Zhengan xifeng（镇肝熄风）Decoction in Preventing and Treating Hypertensive Nephropathy

作     者：张伯科 赵正辉 王汉民 朱军 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志（英文版）)

年 卷 期：1996年第2卷第4期

页      面：270-273页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：hypertension arteriolar nephrosclerosis residual renal function Zhengan Xifeng Decoc-tion 

摘      要：Seventeen cases of hypertensive nephropathy with azotemia (test group) treated with Zhen-gan Xifeng Decoction (ZGXFD) and a routine regimen of Western Medicine were observed. The result wascompared with that of 15 cases treated with routine regimen alone(control. group) . After 3 months of treat-ment, the blood pressure, sodium excretion, blood urea nitrogen and creatinine were all reduced, while cre-atinine clearance rate (CCr) and residual renal function index(RRFI) were improved significantly in bothgroups. Compared with the control group, the treatment on the test group showed a more prominent effect onlowering of diastolic blood pressure, elevating the hemoglobin, reducing the blood level of triglyceride andcreatinine as well as improving on CCr and RRFI , suggesting the deterioration of residual renal function couldbe restrained by ZGXFD , through improving the disorder of lipid metabolism, osmolality gradient and creati-nine kinetics.