Expression and significance of EGFR,C-erbB_2 and PCNA in primary breast carcinoma tissues

作     者：孙治君 

作者机构：Dept Gene Surg1st Affil Hosp Chongqing Med UnivChongqing 400016 

出 版 物：《外科研究与新技术》 (Surgical Research and New Technique)

年 卷 期：2005年第3期

页      面：162-162页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

摘      要：To study the expression of EGFR,C-erbB2 and PCNA in primary breast carcinoma tissues and the value of them in preducting the recurrence of primary breast *** The expression of EGFR,C-erbB2,PCNA in 57 benign and malignant breast paraffin-embedded specimens was detected by using immunohistochemical assay and *** The positive rate of EGFR,C-erbB2,PCNA was increased significantly in malignant breast tissues as compared with benign breast *** positive intensity of PCNA,C-erbB2 was increased significantly is tissues of recurrent breast carcinoma as compared with tissues of no recurrent breast *** The expression of EGFR,C-erbB2 and PCNA may indicate the active proliferation activity of carcinoma *** detection of the overexpression of PCNA and C-erbB2 can predict the recurrence of breast carcinoma and is beneficial to the choose of the treatments.3 refs,4 tabs.