Research and development of airtight biosafety containment facility for stainless steel structures

作     者：Zongxing Zhang Jinhui Wu Enlei Zhang Siqing Zhao Dong Wang Ying Yi Jiancheng Qi 

作者机构：Institute of Medical Service TechnologyAcademy of Military Science PLA ChinaTianjin 300161China National Bio-Protection Engineering Center of ChinaTianjin 300161China Academy of Military MedicineAcademy of Military Sciences PLA ChinaBeijing 100071China Harbin Veterinary Research InstituteChinese Academy of Agricultural SciencesHarbin 150069China 

出 版 物：《Journal of Biosafety and Biosecurity》 (生物安全和生物安保杂志（英文）)

年 卷 期：2019年第1卷第1期

页      面：56-62页

学科分类：081406[工学-桥梁与隧道工程] 08[工学] 0814[工学-土木工程] 082301[工学-道路与铁道工程] 0823[工学-交通运输工程] 

基　　金：This study was supported by the National Key Research And Development Program China(2016YFC1201403) 

主　　题：Biosafety level-4 laboratory Airtightness Containment structure Sealing process 

摘      要：Objective:Airtightness of containment structures of a high-level biosafety laboratory is a critical parameter for preventing leakage of harmful *** aim of this study is to investigate the sealing technology of stainless steel structural airtight biosafety containment ***:An experimental study was conducted on a domestic high-level pathogenic microorganism model laboratory,considering the sealing process of the containment structure,including airtight doors,pass boxes,dunk tanks,through-wall pipeline sealing devices,and sealed floor ***:The results indicate that the airtightness of the model laboratory containment structure meets the tightness requirements of a biosafety level-4(BSL-4)*** also indicate that the construction technology of stainless steel enclosure structures used by the laboratory and the tightness performance and installation process of the developed airtight protective equipment meet the technical requirements of a BSL-4 ***:This successful model laboratory indicates that China has the research and development capacity for stainless steel airtight containment structure manufacturing processes,airtight protective equipment,and technical capacity for independent construction of the highest-level pathogenic microorganism laboratories.