PET radiopharmaceuticals for neuroreceptor imaging

作     者：S. M. AMETAMEY P. A. SCHUBIGER 

作者机构：Center for Radiopharmaceutical Science of ETH PSI and USZ Department of Chemistry and Applied Biosciences of ETH Zurich Switzerland 

出 版 物：《Nuclear Science and Techniques》 (核技术（英文）)

年 卷 期：2006年第17卷第3期

页      面：143-147页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100106[医学-放射医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：PET 放射性药品 大脑受体 碳-11 氟-18 

摘      要：Routine clinical PET radiopharmaceuticals for the noninvasive imaging of brain receptors, transporters, and enzymes are commonly labeled with positron emitting nuclides such as carbon-11 or fluorine-18. Certain minimal conditions need to be fulfilled for these PET ligands to be used as imaging agents in vivo. Some of these prerequisites are discussed and examples of the most useful clinical PET radiopharmaceuticals that have found application in the central nervous system are reviewed.