Intracranial hypotension and co-existent normal-pressure glaucoma： the Beijing intracranial and intraocular pressure study

作     者：LI Zhen YANG Di-ya LU Yan LIU Da-chuan JIA Jian-ping Jonas Jost B WANG Ning-li 

作者机构：Department of Ophthalmology Xuan Wu Hospital CapitalMedical University Beijing 100053 China Department of Neurology Xuan Wu Hospital CapitalMedical University Beijing 100053 China Beijing Tongren Eye Center Beijing Tongren Hospital CapitalMedical University Beijing Ophthalmology & Visual Sciences KeyLaboratory Beijing 100730 China Department of Ophthalmology Medical Faculty Mannheim of theRuprecht-Karls-University Heidelberg Mannheim Germany 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2013年第126卷第8期

页      面：1588-1589页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 0835[工学-软件工程] 081202[工学-计算机软件与理论] 0812[工学-计算机科学与技术（可授工学、理学学位）] 10[医学] 

主　　题：intracranial pressure, glaucoma trans-lamina pressure difference 

摘      要：n contrast to the so-called intraocular pressure, which is .the transcomeal pressure difference, it is thetrans-lamina cribrosa pressure difference, which is of importance for physiology and pathophysiology of the optic nerve head. The trans-lamina cribrosa pressure difference is the difference between the pressure in the intraocular compartment （i.e., the so-called intraocular pressure） minus the retrobulbar pressure, which is formed by the orbital cerebrospinal fluid （CSF）I pressure and the retrobulbar optic nerve tissue pressure. This anatomical fact has been the basis for the speculation that some patients with so-called normal intraocular pressure glaucoma have an abnormally low orbital CSF pressure. Previous clinical studies have supported this hypothesis.2＇3 The purpose of this study is to report on a patient with low CSF pressure and co-existent open-angle glaucoma with normal intraocular pressure.