含分子内氢键的苯硫酚在水相中的Michael加成反应

作     者：高照波 邱雪鹏 郭海泉 康传清 高连勋 

作者机构：中国科学院长春应用化学研究所 

出 版 物：《高等学校化学学报》 (Chemical Journal of Chinese Universities)

年 卷 期：2004年第25卷第8期

页      面：1471-1473,M011页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

主　　题：水相反应 苯硫酚 分子内氢键 Michael加成 

摘      要：The method of Michael addition reaction of thiophenol with intramolecular hydrogen bond in an aqueous medium was reported. The aqueous reactive medium includes saturated sodium bicarbonate solution and catalytic amount of tetrabutylammonium bisulfate. 2-Hydroxythiophenol,2-aminothiophenol,2-carboxythiophenol,ethyl acrylate and arcylonitrile were selected as model molecules to demonstrate the method. It is found that the reaction can be accomplished rapidly at room temperature with a high yield,and no mercapto-coupling byproduct formed.