Tumor-infiltrating B cells come into vogue

作     者：Michael Linnebacher 

作者机构：Division of Molecular Oncology and ImmunotherapyDepartment of General SurgeryUniversity of RostockD-18057 RostockGermany 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第1期

页      面：8-11页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：CD20 + tumor-infiltrating lymphocytes Tumorinfiltrating B cells Prognosis Immunotherapy Functional immunology 

摘      要：Lymphocyte infiltration into solid tumors has been recognized as a main determinator of positive *** the most part this is attributed to cytotoxic T cells capable of directly destroying malignant ***,when considering the complex composition of the human immune system,recent findings of Nielsenet al on a potentially central role of tumor-infiltrating B cells is not really *** this commentary article,I want to highlight the enormous potential impact of this observation for basic and translational research,prognostic procedures and ultimately for the development of future therapeutic concepts.