Burn blister fluids in the neovascularization stageof burn wound healing: A comparison betweensuperficial and deep partial-thickness burn wounds

作     者：Shin-Chen Pan 

作者机构：Department of Surgery Section of Plastic and Reconstructive Surgery National Cheng Kung University Medical College and Hospital Tainan 

出 版 物：《Burns & Trauma》 (烧伤与创伤（英文）)

年 卷 期：2013年第1卷第1期

页      面：27-31页

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 1011[医学-护理学（可授医学、理学学位）] 100214[医学-肿瘤学] 0836[工学-生物工程] 10[医学] 

主　　题：Wound healing angiogenin burn blister fluid neovascularization 

摘      要：Burn wound healing is a complex and dynamic process that involves the interaction between different cell types and mediators. Neovascularization is an imperative stage of wound healing and consists of not only angiogenesis but also adult vasculogenesis. A superficial partial-thickness burn (SPTB) heals within 2 weeks without scarring. A deep partial-thickness burn (DPTB), conversely, requires 2 weeks or longer to heal and requires an aggressive treatment to prevent hypertrophic scarring. Burn blisters on the skin are a hallmark of not only SPTB but also DPTB;however, the effect of burn blister fluids on the neovascularization in these types of burns has not been fully explored. To verify this effect, the role of different burn fluids and the angiogenic factors that modulate this process are currently under investigation.