Synthesis,Characterization and Biocompatibility of Potassium Ferrite Nanoparticles

作     者：Lavanya Khanna N.K.Verma 

作者机构：Nano Research LabSchool of Physics and Materials ScienceThapar University 

出 版 物：《Journal of Materials Science & Technology》 (材料科学技术（英文版）)

年 卷 期：2014年第30卷第1期

页      面：30-36页

核心收录：

学科分类：081702[工学-化学工艺] 07[理学] 070205[理学-凝聚态物理] 08[工学] 0817[工学-化学工程与技术] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0702[理学-物理学] 

基　　金：Department of Science and Technology Government of India New Delhi for awarding her INSPIRE Fellowship 

主　　题：Potassium ferrite nanoparticles Magnetic nanoparticles Superparamagnetic behaviour Biocompatibility Cytotoxicity 

摘      要：In the present study, morphology, size distribution, structure, biocompatibility and magnetic properties of potassium ferrite nanoparticles （KFeO2 NPs）, synthesized by conventional sol-gel method have been reported. The formation of spherical nanoparticles with orthorhombic structure has been confirmed by scanning electron microscopy and X-ray diffraction. The particle size, as obtained by transmission electron microscopy has been found to be in the range of 4-7 nm. Further, the size distribution has been scrutinized using Analyse-it software, where a platykurtic feature in the size distribution was observed. Fourier transform-infrared spectroscopy and thermogravimetric analysis showed the formation of metal （Fe, K） bonds at Neel temperature of 337℃. Vibrating sample magnetometer analysis revealed the superparamagnetic behaviour of the synthesized KFeO2 NPs, with saturation magnetization of 25.72 emu/g. In vitro cytotoxicity test, using MTTassay, on T cell lines （Jurkat cells） showed that KFeO2 NPs are biocompatible at a particle concentration of 100μg/ml.