ATG16L1 and NOD2 polymorphisms enhance phagocytosis in monocytes of Crohn's disease patients

作     者：Simone CS Wolfkamp Caroline Verseyden Esther WM Vogels Sander Meisner Kirsten Boonstra Charlotte P Peters Pieter CF Stokkers Anje A te Velde 

作者机构：Tytgat Institute for Liver and Intestinal Research Academic Medical Center 1105 BK Amsterdam The Netherlands Department of Gastroenterology and Hepatology Academic Medical Center 1105 BK Amsterdam The Netherlands Department of Gastroenterology and Hepatology St. Lucas Andreas Hospital 1105 BK AmsterdamThe Netherlands 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第10期

页      面：2664-2672页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Inflammatory bowel disease Phagocytosis Polymorphism Monocytes Granulocytes Nucleotide-binding ligomerization domain-containing protein 2 Immunity-related guanosine triphosphatase gene Autophagy related like 1 

摘      要：AIM: To investigate if the presence of relevant genetic polymorphisms has effect on the effectual clearance of bacteria by monocytes and granulocytes in patients with Crohn’s disease (CD).