Fluorescence turn-on chemosensor for Hg^(2+) based on a rhodamine derivative and its application in bioimaging

作     者：LIU Chun1,2, ZHOU ZhiGuo2, GAO Yuan2, YANG Hong2, LI BaoGuo1, LI FuYou2 & HUANG ChunHui2 1 School of Chemistry and Chemical Engineering, Inner Mongolia University, Hohhot 010021, China 2 Department of Chemistry, Fudan University, Shanghai 200433, China 

作者机构：School of Chemistry and Chemical Engineering Inner Mongolia University Hohhot 010021 China Department of Chemistry Fudan University Shanghai 200433 China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2009年第52卷第6期

页      面：760-764页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 0802[工学-机械工程] 

基　　金：Supported by the National Natural Science Foundation of China (Grant No. 20801015) Shanghai Leading Academic Discipline Project (Grant No. B108) 

主　　题：chemosensor fluorescence rhodamine bioimaging 

摘      要：A fluorescence turn-on chemosensor based on rhodamine B derivative (FD10) has been developed as a highly sensitive chemosensor for Hg2+. A prominent fluorescence enhancement was measured in the presence of Hg2+, which was in agreement with the changes in the absorption spectrum. Furthermore, by means of laser scanning fluorescence microscopy experiments, it was demonstrated that FD10 was cell-permeable and could be used as a fluorescent probe for monitoring Hg2+ in living cells.