Inhibition of Collagen Synthesis and Regulation of Cell Motility in Vascular Smooth Muscle Cells by Suppression of Connective Tissue growth Factor Expression Using RNAInterference

作     者：Xiao-Jing LIU~1 Huai-Qing CHEN~(1,2)1(Laboratory of Cardiovascular Diseases, West China Hospital, Sichuan University,Chengdu 610041,China)2(Institute of Biomedical Engineering, Sichuan University, Chengdu 610041,China) 

作者机构：Laboratory of Cardiovascular Diseases West China Hospital Sichuan University Chengdu 610041 Chiha Laboratory of Cardiovascular Diseases West China Hospital Sichuan University Chengdu 610041 Chiha Institute of Biomedical Engineering Sichuan University Chengdu 610041 China 

出 版 物：《生物医学工程学杂志》 (Journal of Biomedical Engineering)

年 卷 期：2005年第22卷第S1期

页      面：137-138页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：VSMC CTGF 

摘      要：1 IntroductionVascular smooth muscle cell (VSMC) hyperplasia plays an important role in both chronic and acute pathologies including atherosclerosis and restenosis. Recent studies have shown that connective tissue growth factor (CTGF) is a novel growth factor involved in the development and progression of atherosclerosis.