Effects of Mycoestrogens on Female Reproduction

作     者：Christian Lee Andersen Fei Zhao Xiao-Qin Ye 

作者机构：Department of Physiology and PharmacologyCollege of Veterinary MedicineUniversity of GeorgiaAthensGA 30602USA Interdisciplinary Toxicology ProgramUniversity of GeorgiaAthensGA 30602USA Reproductive Developmental Biology GroupNational Institute of Environmental Health SciencesDurhamNC 27709USA 

出 版 物：《Reproductive and Developmental Medicine》 (生殖与发育医学（英文版）)

年 卷 期：2018年第2卷第1期

页      面：52-58页

学科分类：0710[理学-生物学] 100405[医学-卫生毒理学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学] 

基　　金：the National Institutes of Health(NIH R01HD065939[co-funded by ORWH and NICHD]to XY)for financial support in the form of assistantship and grant support 

主　　题：Female Reproduction Mycoestrogens Puberty Zearalenone 

摘      要：Zearalenone(ZEA)is produced by Fusarium species and a common contaminant in *** and its metabolites,α-andβ-zearalenol,α-andβ-zearalanol,and zearalanone,are mycoestrogens that can interfere with estrogen *** levels of mycoestrogens reduced female fertility in farm animals and rodents,in which adverse effects of mycoestrogens on major events in female reproduction,including ovarian folliculogenesis,ovulation,ovarian steroidogenesis,fertilization,preimplantation embryo development and transport,embryo implantation,placentation,parturition,and lactation,have been reported in different experimental ***,we review the in vivo effects of mycoestrogens on the main events in female reproduction.