Synthesis and Crystal Structure of Chiral 4-Hydroxy-4-butyrolactam Fused Aziridine

作     者：WANG Jian-Ping WANG Jian-Ge FU Yong-Ju LI Ying-Fei 

作者机构：Department of Chemistry Luoyang Normal University Luoyang 471022 China Chemical Engineering ＆ Pharmaceutics College Henan University of Science and Technology Luoyang 471003 China 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2008年第27卷第2期

页      面：133-136页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Project supported by key subject of Luoyang Normal University (No. 2004yzk90) 

主　　题：butyrolactam aziridine asymmetric synthesis crystal structure 

摘      要：A novel compound of chiral 4-hydroxy-4-butyrolactam fused aziridine was synthesized via tandem nucleophilic displacement reaction under mild condition. Its structure was determined by IR, 1H NMR, elemental analysis and X-ray diffraction. The crystal of the new compound is of orthorhombic, space group P212121 with a = 6.4246（6）, b = 13.5081（13）, c = 18.6399（18） A, Mr = 278.39, Z = 4, V = 1617.6（3）A^3, Dc = 1.143 g/cm^3, p（MoKa） = 0.075 mm^-1, F（000） = 608, the final R = 0.0297 and wR = 0.0679.