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Cholangiographic characteristics of common bile duct dilatation in children

Cholangiographic characteristics of common bile duct dilatation in children

作     者:Seak Hee Oh Soo-Hee Chang Hyun Jin Kim Jin Min Cho Ji-Hee Hwang Jung-Man Namgoong Dae Yeon Kim Young-Ah Cho Chong Hyun Yoon Kyung Mo Kim 

作者机构:Department of PediatricsAsan Medical Center Children’s HospitalUniversity of Ulsan College of Medicine Department of Pediatric SurgeryAsan Medical Center Children’s HospitalUniversity of Ulsan College of Medicine Department of Pediatric RadiologyAsan Medical Center Children’s HospitalUniversity of Ulsan College of Medicine 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2015年第21卷第20期

页      面:6229-6235页

核心收录:

学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 100207[医学-影像医学与核医学] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术(可授医学、理学学位)] 100202[医学-儿科学] 100106[医学-放射医学] 10[医学] 100602[医学-中西医结合临床] 

主  题:Endoscopic retrograde cholangiopancreatography Common bile duct Choledochal cyst Choledolithiasis Children 

摘      要:AIM: To investigate whether children with congenital common bile duct dilatation(CBDD) differ from children with obstructive CBDD in cholangiographic ***: In this retrospective cohort study, the baseline data and the results of imaging analyses were reviewed among children who had endoscopic retrograde cholangiopancreatography(ERCP) due to CBDD. ERCP was performed on all pediatric patients by experienced pediatric endoscopists. The maximal transverse diameter of the common bile duct(CBD) was measured on ERCP. To assess whether ageadjusted CBDD could be used for differential diagnosis, a CBDD severity index(SI) was calculated by dividing the measured CBD diameter by the age-corrected maximal diameter of a normal CBD. RESULTS: A retrospective medical chart review revealed that 85 consecutive children under 16 years of age with hepatobiliary disease and CBDD were referred to Seoul Asan Medical Center. Fiftyfive(64.7%) children had congenital CBDD and 30(35.3%) had obstructive CBDD. The two groups did not differ significantly in terms of clinical characteristics except for sex. The congenital and obstructive CBDD groups did not differ significantly in terms of mean CBD diameter(19.3 ± 9.6 mm vs 12.2 ± 4.1 mm, P 0.05). However, congenital CBDD cases had a significantly higher mean SI than obstructive CBDD cases(3.62 ± 1.64 vs 1.98 ± 0.71, P = 0.01). In multivariate analysis, an SI value ≥ 2.32 and comorbidity with anomalous union of pancreaticobiliary duct(APBDU) in ERCP independently predicted congenital ***: Measuring the CBD may aid the differential diagnosis of both CBDD and APBDU in children.

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