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A case of long survival in poorly differentiated small cell carcinoma of the pancreas

A case of long survival in poorly differentiated small cell carcinoma of the pancreas

作     者:Min Sung Chung Tae Kyung Ha Kyeung Geun Lee Seung Sam Paik 

作者机构:Department of Surgery College of Medicine Hanyang University Seoul 133-792 South Korea Department of Pathology College of Medicine Hanyang University Seoul 133-792 South Korea 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2008年第14卷第31期

页      面:4964-4967页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Small cell carcinoma Pancreas Pancreatic carcinoma Extrapulmonary 

摘      要:Small cell carcinoma (SCC) of the pancreas is rare. It has similar histological features to pulmonary small cell carcinoma and is equally aggressive. Most patients with SCC in the pancreas reported in case studies died within 1 year after diagnosis. We present a case of unusually long-term survival after surgery and combined chemotherapy for SCC of the pancreas. A 62-year-old woman presented with epigastric pain and jaundice. Computed tomography revealed dilated common bile duct caused by external compression of the mass in the pancreatic head. Exploratory laparotomy and pancreaticoduodenectomy (PPPD) was performed with histopathological analysis confirming a primary small cell carcinoma of the pancreas. After an uneventful postoperative recovery, the patient was treated with 6 cycles of combined chemotherapy consisting of cisplantin and ectoposide. During the follow-up, there was no evidence of recurrence and the patient has remained in a good health condition for 36 mo since the diagnosis.

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