Gut microbiome: a key player in cancer immunotherapy

作     者：Yasuyuki Shigematsu Kentaro Inamura 

作者机构：Division of PathologyThe Cancer InstituteDepartment of PathologyThe Cancer Institute HospitalJapanese Foundation for Cancer ResearchTokyoJapan 

出 版 物：《Hepatobiliary Surgery and Nutrition》 (肝胆外科与营养（英文）)

年 卷 期：2018年第7卷第6期

页      面：479-480页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：immunity Immune inhibiting 

摘      要：Immune checkpoint inhibitors(ICIs)have revolutionized the therapeutic approaches used to treat *** checkpoint molecules located on tumor cells interact with receptors on cytotoxic CD8+T cells(a type of effector T lymphocyte)and consequently lead to evasion of tumor cells from the immune *** stimulate T cellmediated antitumor immunity by inhibiting the interactions between immune checkpoint molecules and inhibitory T cell receptors.