双气囊内镜可检测到表现为多个溃疡瘢痕的回肠黏膜相关淋巴组织淋巴瘤

作     者：Yoshida N. Wakabayashi N. Nomura K. 陈云茹 

作者机构：Dept. Molec. Gastr oenterol./Hepatol. Kyoto Prefectural Univ. of Medicine Graduate School of Medical Science Kawaramachi-Hirokoji Kamigyo-ku Kyoto 6028566 JapanDr. 

出 版 物：《世界核心医学期刊文摘（胃肠病学分册）》 (Core Journals in Gastroenterology)

年 卷 期：2005年第1卷第4期

页      面：25-25页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：病理学检查 免疫组化分析 非典型淋巴细胞 固有肌层 闪烁扫描 淋巴瘤 瘤细胞 活检标本 结肠镜 血管造影 

摘      要：A 72-year-old man was admitted to our hospital to undergo a novel small-intestinal endoscopic procedure. He had had occasional episodes of hematochezia over a 2-year period, during which he had been hospitalized twice previously. However, numerous investigations, including hematological and biochemical studies, gastroscopy, colonoscopy, computed tomography, scintigraphy, and angiography had failed to detect the source of bleeding in the gastrointestinal tract. On this a dmission,double-balloon enteroscopy was performed and revealed several ulcer scars with localized dilation of the ileum. Histopathological examination of the biopsy specimens reveled no abnormal finding. Partial resection of the ileum was performed to prevent further gastrointestinal bleeding, and histopathological examination of the resected specimen revealed aggregation of atypical lymphocytes, predominantly in the muscularis propria layer. Immunohistochemical examination demonstrated that the tumor cells were positive for CD20 and BCL2, but negative for UCHL1. Based on these findings, the lesion was diagnosed as a marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue. Eighteen months after surgery, the patient was still in complete remission.