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A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support

A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support

作     者:Meng Gao Cui Fen Lu Gui Chun Yang Zu Xing Chen 

作者机构:Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering Hubei University Wuhan 430062 China 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2011年第22卷第7期

页      面:823-826页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 070205[理学-凝聚态物理] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程(可授工学、理学学位)] 0703[理学-化学] 0702[理学-物理学] 

基  金:the Natural Sciences Foundation of Hubei province in China(Nos.2007ABA031 and 2008CDA078) 

主  题:Onium salt Support Synthesis Pyridazines 

摘      要:In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-aryl-2,5- dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.

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