Antifungal activity of various essential oils against Saccharomyces cerevisiae depends on disruption of cell membrane integrity
作者机构：Department of BioengineeringGebze Technical UniversityKocaeliTurkey
出 版 物：《BIOCELL》 (生物细胞（英文）)
年 卷 期：2017年第41卷第1期
页 面：13-18页
核心收录：
学科分类：081803[工学-地质工程] 08[工学] 0818[工学-地质资源与地质工程]
主 题：Saccharomyces cerevisiae Essential oils Antifungal activity Cell membrane
摘 要：Antifungal activity and mode of action of nine essential oils(EOs)against *** cells were *** effects of commercial lemon peel,orange peel,tea tree,turpentine,rosemary,peppermint,thyme,oregano and clove oils were determined through Minimum Inhibitory Concentration(MIC),Minimum Fungicidal Concentration(MFC)and inhibition zone *** most effective oil was turpentine *** peel,thyme and oregano oils were also effective,according to MIC and *** zone measurements,also revealed oregano,orange peel,thyme,turpentine and clove oils as most efficient ***,membrane damage of yeast cells was studied by measuring the extracellular pH and conductivity in a concentration dependent *** peel,turpentine,thyme and oregano oils caused a clear increase in extracellular pH of glucose-induced yeast cells and induced an increase in extracellular *** results point to the deterioration of yeast cell membrane integrity upon exposure to *** these oils can be used as food preservatives and pharmaceutical agents,it is very important to understand their mode of action and their main target sites in the *** this research not only opens new perspectives to understand antifungal activity mechanisms of EOs,but also help widen their use.
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