Magnetic nanoparticle-based cancer therapy

作     者：余靓 黄冬雁 Muhammad Zubair Yousaf 侯仰龙 高松 

作者机构：Department of Materials Science and EngineeringCollege of EngineeringPeking University Department of Otorhinolaryngology Head & Neck SurgeryClinical Division of SurgeryChinese PLA (People's Liberation Army) General Hospital College of Chemistry and Molecular EngineeringPeking University 

出 版 物：《Chinese Physics B》 (中国物理B（英文版）)

年 卷 期：2013年第22卷第2期

页      面：23-35页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Project supported by the National Natural Science Foundation of China (Grant Nos. 51125001,51172005,and 90922033) the Research Fellowship for International Young Scientists of the National Natural Science Foundation of China (Grant No. 51250110078) the Doctoral Program of the Education Ministry of China (Grant No. 20120001110078) PKU COE-Health Science Center Seed Fund 

主　　题：magnetic nanoparticles cancer therapy hyperthermia drug delivery targeting magnetic reso-nance imaging 

摘      要：Nanoparticles（NPs） with easily modified surfaces have been playing an important role in *** cancer is one of the major causes of death,tremendous efforts have been devoted to advance the methods of cancer diagnosis and ***,magnetic nanoparticles（MNPs） that are responsive to a magnetic field have shown great promise in cancer *** with traditional cancer therapy,magnetic field triggered therapeutic approaches can treat cancer in an unconventional but more effective and safer *** this review,we will discuss the recent progress in cancer therapies based on MNPs,mainly including magnetic hyperthermia,magnetic specific targeting,magnetically controlled drug delivery,magnetofection,and magnetic switches for controlling cell *** recently developed strategies such as magnetic resonance imaging（MRI） monitoring cancer therapy and magnetic tissue engineering are also addressed.