软X线治疗皮肤基底细胞癌和鳞状细胞癌
Soft x-ray therapy for cutaneous basal cell and squamous cell carcinomas作者机构：In der Stroth 37 D-48157 M nster Germany Dr
出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期：2006年第2卷第3期
页 面：11-12页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：皮肤基底细胞癌 鳞状细胞癌患者 X线治疗 恶性肿瘤 溃疡形成 剂量分次 肿瘤复发率 连续照射 照射剂量 文献报道
摘 要：Background: We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. Objective: We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. Methods: Patients with 1267 consecutively irradiated (1988- 1992) basal cell and squamous cell carcinomas were followed up (average 77months). Results: The recurrence rate (5.1% ) was related to tumor size and thickness and to the time-dose-fractionation factor. The frequency of ulcerations (6.3% ) depended on field size, hardness of the x-rays, and in smaller fields (diameter up to 4 cm) on total dose, and time-dose-fractionation factor. Of all ulcerations, 82.5 % could be conservatively cured. Limitations: We have no evidence that our radiation schedule is superior to those published by other authors. Conclusion: These results verify the
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