Double-vessel verylate stent thrombosis following Resolute Onyx zotarolimus eluting stents implantation in an octogenarian

作     者：George Kassimis Tushar Raina 

作者机构：Department of CardiologyCheltenham General HospitalGloucestershire Hospitals NHS Foundation TrustCheltenhamUnited Kingdom Second Department of CardiologyHippokration HospitalMedieal SchoolAristotle University of ThessalonikiThessalonikiGreece 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2018年第15卷第10期

页      面：639-643页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

主　　题：Double vessel occlusion Myocardial infarction Very late stent thrombosis Zotarolimus eluting stents 

摘      要：Compared with bare-metal stents (BMS),drug-eluting stems (DES)have shown better clinical outcomes for pa- tients undergoing percutaneous coronary intervention (PCI) by inhibition of neo-intirnal hyperplasia.[1]However,early- generation DES produced late thrombotic events,more than l-year,by delaying arterial healing of stented vessels,[2-5] New-generation DES have been developed with thinner stent struts,more biocompatible polymer coatings for drug release,and a variety of antiproliferative agents with similar or superior anti-restenotic efficacy.[6]This development has led to a significant improvement in the efficacy and safety of new-generation DES,and consistently lower rates of very late stent thrombosis (VLST).[7,8]In fact,use of new-ge- neration DES is the standard treatment in contemporary PCI practice.[9]