Investigation of glucose concentration measurement based on tunable pulsed laser induced photoacoustic technique

作     者：任重 刘国栋 黄振 

作者机构：Key Laboratory of Optic-electronic and Communication Jiangxi Science and Technology Normal University Nanchang 330038 China 

出 版 物：《Chinese Optics Letters》 (中国光学快报（英文版）)

年 卷 期：2013年第11卷第14期

页      面：88-91页

核心收录：

学科分类：080903[工学-微电子学与固体电子学] 0832[工学-食品科学与工程（可授工学、农学学位）] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 083202[工学-粮食、油脂及植物蛋白工程] 

基　　金：This work was supported by the National Natural Science Foundation of China (No. 61068002)  the Natural Science Foundation of Jiangxi Province (No. 20114BAB215047)  the Science and Technology Pillar Program of Jiangxi Province (No. 20132BBGT0103) and the Scientific Research Foundation of Jiangxi Provincial Education Bureau (No. GJJ12594) 

主　　题：000.1430 Biology and medicine 170.1420 Biology 170.1470 Blood or tissue constituent monitoring 

摘      要：A tunable pulsed laser induced photoacoustic （PA） measurement set-up is established in the forward mode to monitor in vitro glucose concentration. A series of experiments are investigated to verify the feasibility of this set-up and scheme. Peak-to-peak values （PPVs） of several glucose aqueous solutions are recorded and averaged 512 times at each wavelength. Experimental results demonstrate that the time-resolved PA profile of glucose solutions has a good agreement with the PA theories. The characteristic wavelengths of glucose solution are determined via differential method. The root-mean-square error （RMSE） of predicted concentration reaches 3.15 mg/dl at the optimum wavelength of 1 510 nm via least square （LS） fitting algorithm.