Animal models of axon regeneration after spinal cord injury
Animal models of axon regeneration after spinal cord injury作者机构:University of Miami School of Medicine Miami Project to Cure Paralysis Department of Neurological Surgery
出 版 物:《Neuroscience Bulletin》 (神经科学通报(英文版))
年 卷 期:2013年第29卷第4期
页 面:436-444页
核心收录:
学科分类:1002[医学-临床医学] 100210[医学-外科学(含:普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
基 金:supported by NiNDS 1R01NS081040-01,1R21NS082835-01 US Army W81XWH1010737 The Miami Project to Cure Paralysis Buoniconti Fund
主 题:pyramidotomy strain differences contusion injury models
摘 要:With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. In this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.