Small intestine bleeding due to multifocal angiosarcoma

作     者：Luisa Zacarias Fhrding Arne Macher Stefan Braunstein Wolfram Trudo Knoefel Stefan Andreas Topp 

作者机构：Department of GeneralVisceral and Pediatric SurgeryHeinrich-Heine-UniversityDüsseldorfMoorenstrasse 540225 DüsseldorfGermany Institute of PathologyHeinrich-Heine-UniversityDüsseldorfMoorenstrasse 540225 DüsseldorfGermany 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2012年第18卷第44期

页      面：6494-6500页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Gastrointestinal bleeding Small intestine Angiosarcoma Small intestinal neoplasm 

摘      要：We report a case of an 84-year-old male patient with primary small intestinal *** patient initially presented with anemia and *** endoscopy revealed no signs of upper or lower active gastrointestinal *** patient had been diagnosed 3 years previously with an aortic dilation,which was treated with a *** tomography suggested an aorto-intestinal fistula as the cause of the intestinal bleeding,leading to operative stent explantation and aortic ***,an aorto-intestinal fistula was not found,and the intestinal bleeding did not arrest *** constant need for blood transfusions made an exploratory laparotomy imperative,which showed multiple bleeding sites,predominately in the jejunal wall.A distal loop jejunostomy was conducted to contain the small intestinal bleeding and a segmental resection for histological evaluation was *** histological analysis revealed a lessdifferentiated tumor with characteristic CD31,cytokeratin,and vimentin expression,which led to the diagnosis of small intestinal ***,the infiltrated part of the jejunum was successfully resected in a subsequent operation,and adjuvant chemotherapy with paclitaxel was *** of the small intestine is an extremely rare malignant neoplasm that presents with bleeding and high *** diagnosis and treatment are essential to improve outcome.A small intestinal angiosarcoma is a challenging diagnosis to make because of its rarity,nonspecific symptoms of altered intestinal function,nonspecific abdominal pain,severe melena,and acute abdominal ***,a quick clinical and histological diagnosis and decisive measures including surgery and adjuvant chemotherapy should be the aim.