Overexpression of P-glycoprotein in hepatocellular carcinoma and its clinical implication

作     者：Kong XB Yang ZK Liang LJ Huang JF Lin HL 

作者机构：Department of SurgeryThe First Affiliated HospitalChongqing University of Medical SciencesChongqing 400016China Division of Hepatobiliary SurgeryThe First Affiliated HospitalSun Yat-Sen University of Medical SciencesGuangzhou 510080Guangdong ProvinceChina Departrnent of PathologySun Yat-Sen University of Medical SciencesGuangzhou 510089Guangdong ProvinceChina 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2000年第6卷第1期

页      面：134-135页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：the China Medical Board of New York Inc. USA Grant No.90-534 

主　　题：Subject headings liver neoplasms carcinoma hepatocellular P-glycoprotein multidrug resistance-1 gene immunohistochemistry 

摘      要：INTRODUCTIONMost advanced hepatocellular garcinoma (HCC) isinsensitive to most anticancer drugs which might berelated to the high frequency of expression of themultidrug resistance-1(MDR1) gene and itsproduct,P-glycoprotein (p-gp).p-gp expressionmay also be concerned with tumor progression *** the present study。