Design,synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6-yl]methyl-amino)benzoate derivatives
Design,synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6-yl]methyl-amino)benzoate derivatives作者机构:Department of Organic ChemistryAndhra UniversityVisakhapatnam 530003India DRDO - HQNew Delhi 110011India
出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期:2011年第22卷第5期
页 面:567-570页
核心收录:
学科分类:1007[医学-药学(可授医学、理学学位)] 0703[理学-化学] 10[医学]
基 金:Defence Research and Development Organisation DRDO
主 题:Isatin Schiff base Mannich base Antibacterial activity
摘 要:A series of new methyl-4-((substituted phenyl)[6H-indolo(2,3-b)quinoxalin-6yl]methylamino)benzoate derivatives have been synthesized and assayed for their antibacterial activity on 9 different bacterial *** the screened compounds 2e-2g exhibited potent inhibitory activity compared to standard drug employed,worth further investigation.