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Synthesis, Dimeric Crystal Structure, and Biological Activities of N-(4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N′-(2-trifluoromethyl-phenyl)-guanidine

Synthesis, Dimeric Crystal Structure, and Biological Activities of N-(4-Methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N′-(2-trifluoromethyl-phenyl)-guanidine

作     者:HE Feng-qi WANG Bao-lei LI Zheng-ming 

作者机构:Elemento-Organic Chemistry Institute State-Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin 300071 P. R. China 

出 版 物:《Chemical Research in Chinese Universities》 (高等学校化学研究(英文版))

年 卷 期:2006年第22卷第6期

页      面:768-771页

核心收录:

学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基  金:Supported by the National Basic Research Program of China(No. 2003CB114406) 

主  题:Ketol-acid reductoisomerase Synthesis X-ray diffraction Crystal structure Biological activity 

摘      要:The title compound, N-(4-methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl)-N'-(2-tritluoromethyl-phenyl)-guanidine, was synthesized and its structure was confirmed by using IR, MS,^1H NMR, and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound has a weak herbicidal activity.

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