Metabolic signaling functions of the heme oxygenase/CO system in metabolic diseases

作     者：Hyo Jeong Kim Yeonsoo Joe Young-Joon Surh Hun Taeg Chung 

作者机构：Department of Biological SciencesUniversity of UlsanUlsanSouth Korea Tumor Microenvironment Global Core Research CenterResearch Institute of Pharmaceutical SciencesSeoul National UniversitySeoulSouth Korea 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2018年第15卷第12期

页      面：1085-1087页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：This work was supported by the Priority Research Centers Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education(2014R1A6A1030318) 

主　　题：system monoxide oxidative 

摘      要：Immunometabolism is the intersection of immunology and *** heme oxygenase(HO)-1 and carbon monoxide(CO)(HO-1/CO)system can be induced by various stresses,including infection,and its function is to relieve stresses such as oxidative and inflammatory *** we demonstrate that the HO-1/CO system is intimately involved in the beneficial modulation of metabolic pathways via the production of ATF4 through an integrative stress response.